Thromboxane Biosynthesis and Platelet Function in Type II Diabetes Mellitus
Open Access
- 21 June 1990
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 322 (25) , 1769-1774
- https://doi.org/10.1056/nejm199006213222503
Abstract
It has been suggested that platelet hyperreactivity in patients with diabetes mellitus is associated with increased platelet production of thromboxane. We therefore compared the excretion of a thromboxane metabolite and platelet function in 50 patients with Type II diabetes mellitus who had normal renal function and clinical evidence of macrovascular disease and in 32 healthy controls.This publication has 24 references indexed in Scilit:
- Thromboxane Biosynthesis and Platelet Function in Type I Diabetes MellitusNew England Journal of Medicine, 1988
- Radioimmunoassay of 11-dehydrothromboxane B2 in human plasma and urineBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1987
- Platelet Activation in Unstable Coronary DiseaseNew England Journal of Medicine, 1986
- Platelet function during continuous insulin infusion treatment in insulin-dependent diabetic patientsDiabetes, 1985
- Functional significance of renal prostacyclin and thromboxane A2 production in patients with systemic lupus erythematosus.Journal of Clinical Investigation, 1985
- Platelets and Diabetes MellitusNew England Journal of Medicine, 1984
- Analysis of prostacyclin and thromboxane biosynthesis in cardiovascular disease.Circulation, 1983
- Selective Cumulative Inhibition of Platelet Thromboxane Production by Low-dose Aspirin in Healthy SubjectsJournal of Clinical Investigation, 1982
- Inhibition of platelet prostaglandin synthetase by oral aspirin.Journal of Clinical Investigation, 1978
- Aggregation of Blood Platelets by Adenosine Diphosphate and its ReversalNature, 1962