Enantioselective Claisen Rearrangements with a Hydrogen-Bond Donor Catalyst
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- 25 June 2008
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 130 (29) , 9228-9229
- https://doi.org/10.1021/ja803370x
Abstract
N,N′-Diphenylguanidinium ion associated with the noncoordinating BArF counterion is shown to be an effective catalyst for the [3,3]-sigmatropic rearrangement of a variety of substituted allyl vinyl ethers. Highly enantioselective catalytic Claisen rearrangements of ester-substituted allyl vinyl ethers are then documented using a new C2-symmetric guanidinium ion derivative.Keywords
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