SPLITTING OF ε-CAPROLACTAM AND OTHER LACTAMS BY BACTERIA
- 1 March 1966
- journal article
- research article
- Published by Oxford University Press (OUP) in Plant and Cell Physiology
- Vol. 7 (1) , 105-114
- https://doi.org/10.1093/oxfordjournals.pcp.a079155
Abstract
ε-Caprolactam-utilizing bacteria split ε-caprolactam, δ-valerolactam and γ-butyrolactam, and produce the ω-amino acids corresponding to them. This activity is lost when cells are grown on 6-amino-caproic acid or ammonium adipate, and reappears when cells are incubated with either ε-caprolactam or δ-valerolactam as the sole major organic nutrient. Chloramphenicol inhibits this adaptation. The enzyme splitting those lactams is one and the same. It may be called “lactam-splitting enzyme”. But attempts to demonstrate the enzymic activity in a cell-free system has not yet been successful.This publication has 2 references indexed in Scilit:
- BACTERIAL BREAKDOWN OF ε-CAPROLACTAM AND ITS CYCLIC OLIGOMERSPlant and Cell Physiology, 1966
- METABOLISM OF 2-PYRROLIDONE AND γ-AMINOBUTYRIC ACID BY PSEUDOMONAS AERUGINOSAJournal of Bacteriology, 1958