Reduction of pain response in premature infants using intraoral sucrose.
Open Access
- 1 March 1996
- journal article
- clinical trial
- Published by BMJ in Archives of Disease in Childhood: Fetal & Neonatal
- Vol. 74 (2) , F126-F128
- https://doi.org/10.1136/fn.74.2.f126
Abstract
The potential of sucrose to reduce the pain response in a group of healthy premature infants was investigated. Fifteen infants of 32-34 weeks postmenstrual age were tested in a blind crossover manner on two separate occasions no more than two days apart. Either 1 ml of 25% sucrose solution or sterile water was syringed into the baby's mouth 2 minutes before routine heel lancing. Response to the painful stimuli was measured by duration of cry and by facial expression (pain score). There was a significant reduction in the duration of first cry, the percentage of time spent crying in the 5 minutes after heel prick, and the pain score in the sucrose treated group. It is concluded that sucrose has analgesic effects in healthy premature infants.Keywords
This publication has 20 references indexed in Scilit:
- EFFECTS OF INTRA‐ORAL SUCROSE ON CRYING, MOUTHING AND HAND‐MOUTH CONTACT IN NEWBORN AND SIX‐WEEK‐OLD INFANTSDevelopmental Medicine and Child Neurology, 1994
- Behavioural response to pain in healthy neonates.Archives of Disease in Childhood: Fetal & Neonatal, 1994
- Effect of sucrose on crying in response to heel stab.Archives of Disease in Childhood, 1993
- Human development and umami tastePhysiology & Behavior, 1991
- Developmental Change of Sucking Response to Taste in InfantsNeonatology, 1991
- Why do sugars taste good?Neuroscience & Biobehavioral Reviews, 1990
- A new method for delivering a taste without fluids to preterm and term infantsDevelopmental Psychobiology, 1990
- POSTNATAL DEVELOPMENT OF THE CUTANEOUS FLEXOR REFLEX: COMPARATIVE STUDY OF PRETERM INFANTS AND NEWBORN RAT PUPSDevelopmental Medicine and Child Neurology, 1988
- Pain and Its Effects in the Human Neonate and FetusNew England Journal of Medicine, 1987
- Interactions between sucrose, pain and isolation distressPharmacology Biochemistry and Behavior, 1987