Clinical Role of Blood Levels

Abstract
The impact of drug level monitoring on practice and quality of therapy is discussed. Analysis of the literature and a more detailed discussion of three model drugs (salicylates, digoxin, and theophylline) show a surprisingly low degree of attention to the problem of evaluating the clinical relevance of a drug monitoring program through controlled studies and techniques. There is a potential, and possibly already existing, gap between clinical pharmacokinetics and routine therapy. Closer assessment of these points, with emphasis on educational programs, should be considered among the frontiers leading to a better integration of therapeutic monitoring into medical practice.

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