[18F]‐Dopa positron emission tomography imaging in early‐stage, non‐parkin juvenile parkinsonism
- 22 July 2002
- journal article
- case report
- Published by Wiley in Movement Disorders
- Vol. 17 (4) , 789-794
- https://doi.org/10.1002/mds.10133
Abstract
There are few reports of positron emission tomography (PET) in juvenile parkinsonism (JP). We report on the results of 18F‐6‐fluoro‐L‐dopa (FD) PET in a 14‐year‐old patient with JP of 5 years duration associated with atypical features. This is the youngest subject to be investigated to date. There was a severe asymmetric reduction in striatal FD uptake, with a rostrocaudal gradient in the putamen similar to that seen in adult‐onset idiopathic parkinsonism. Extensive DNA analysis in this patient did not show mutations in the parkin gene. © 2002 Movement Disorder SocietyKeywords
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