Synthesis of aminocyclitol moieties of trehalase inhibitors, trehalostatin and trehazolin. Confirmation of the correct structure of the inhibitor
- 1 January 1992
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 15,p. 1939-1942
- https://doi.org/10.1039/p19920001939
Abstract
The respective aminocyclitol moieties 3a and 4a of trehalostatin 1 and trehazolin 2, potent trehalase inhibitors, have been synthesized as the penta-N,O-acetyl derivatives 3b and 4b by racemic modification. The latter was shown to be identical to the equivalent derivative obtained from 2 on the basis of the 1H NMR spectra, confirming the correct structure of the inhibitor.Keywords
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