Time-Dose-Volume Relationship in Hodgkin's Disease

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Abstract
A tumor dose of about 3,500 to 4,000 rads in 4 weeks offers a good chance of local control even for large tumors. If the shorter treatment time is desired, however, a relatively higher dose than usually suggested has to be delivered, and 1,250 rads in 2 treatments at a 24-hr. interval will give a good chance of permanent local control. The dose which may be delivered to a given area depends on the patient''s condition as well as on the site of disease, and it may be necessary to use intermediate doses and treatment times to decrease the reaction in the normal tissues. A lower dose should be sufficient for small tumors and prophylactic treatment.

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