Relationship between Antidepressant Effect and Plasma Level of Nortriptyline. Clinical Studies.*
- 1 January 1976
- journal article
- research article
- Published by Georg Thieme Verlag KG in Pharmacopsychiatry
- Vol. 9 (01) , 27-32
- https://doi.org/10.1055/s-0028-1094474
Abstract
Strong evidence has been found for the assumption that NT inhibits its own antidepressive effect at high, but non toxic plasma levels in patients suffering from endogenous depression. Based on three investigations we will recommend an optimal therapeutic plasma range for NT between 50 and 150 ng NT/ml. * Anna-Monika Lecture, München 1975 Viele Befunde sprechen dafür, daß Nortryptilin in endogen-depressiven Patienten bei hohen, nicht toxischen Plasmaspiegeln seinen eigenen antidepressiven Effekt hemmt. Auf der Grundlage von drei Untersuchungen empfehlen wir einen optimalen Nortriptylin-Plasmaspiegel zwischen 50 und 150 ng/mLKeywords
This publication has 0 references indexed in Scilit: