Neuropathologic findings in a Guillain–Barré patient with strokes after IVIg therapy
- 13 August 2002
- journal article
- case report
- Published by Wolters Kluwer Health in Neurology
- Vol. 59 (3) , 458-461
- https://doi.org/10.1212/wnl.59.3.458
Abstract
Strokes have been rarely associated with immunoglobulin G (IVIg) therapy. A 70-year-old woman with stable polycythemia vera developed Guillain–Barré syndrome and received IVIg, 8 days following which she became comatose due to bilaterally symmetric cerebral infarcts. Autopsy showed intravascular aggregates of fibrin-IgG but also platelets and a necrotizing microangiopathy in the infarcts.Keywords
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