Sensitivity to Pork-Liver Extract in Pernicious Anemia

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Abstract
NOT until several years after the classic report of Minot and Murphy1 on the treatment of pernicious anemia with liver was a potent injectable liver extract first employed for the routine therapy of this disease. In 1933 Gänsslen2 gave scant details of the method of preparation but described striking hematologic and clinical effects with the product later well known under the proprietary name of "Campolon." Subsequently, the cases of at least 175 patients who were sensitive to liver extract have been reported, half of them in the last three years. Individual studies indicate that such sensitivity is not a rare . . .

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