Effect of liposomes containing cholesterol on a hepatic cholesterol-7a-hydroxylase and drug oxidation system
- 1 January 1981
- journal article
- research article
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 37 (1) , 81-83
- https://doi.org/10.1007/bf01965584
Abstract
A statistically significant increase (p<0.01) in the activities of the microsomal enzymes cholesterol-7a-hydroxylase (EC 1.14.13.17), biphenyl-4-hydroxylase, aniline hydroxylase, NADPH-cytochrome-c-reductase (EC 1.6.2.4) and p-nitroanisole-O-demethylase, was shown in cholesterol-loaded rat liver microsomes. The data indicate that profound functional changes are induced in membrane proteins by exogenous cholesterol.This publication has 16 references indexed in Scilit:
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