Insulin-Dependent Diabetes: A Disease of Autoaggression
- 2 April 1976
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 192 (4234) , 64-66
- https://doi.org/10.1126/science.769160
Abstract
Lymphocytes from patients with insulin-dependent diabetes demonstrated significant cytoadherence and cytotoxicity against human insulinoma cells in vitro as compared to lymphocytes from normals. Complement was not involved in insulinoma cell destruction. The findings suggest that insulin-dependent diabetes may be a disease of autoaggression.This publication has 13 references indexed in Scilit:
- Diabetes: Epidemiology Suggests a Viral ConnectionScience, 1975
- Cell-mediated Immunity in Diabetes Mellitus Lymphocyte Transformation by Insulin and Insulin Fragments in Insulin-treated and Newly-diagnosed DiabeticsDiabetes, 1975
- ANTIBODIES TO PANCREATIC ISLET CELLS IN INSULIN-DEPENDENT DIABETICS WITH COEXISTENT AUTOIMMUNE DISEASEThe Lancet, 1974
- Antibody-Dependent Cytotoxicity Mediated by Human Fc-Receptor-Bearing Cells Lacking Markers for B- and T-LymphocytesInternational Archives of Allergy and Immunology, 1974
- Adrenocortical insufficiencyClinics in Endocrinology and Metabolism, 1972
- Antipancreatic Cellular Hypersensitivity in Diabetes MellitusDiabetes, 1971
- The Glomerular Permeability Determined by Dextran Clearance Using Sephadex Gel FiltrationScandinavian Journal of Clinical and Laboratory Investigation, 1968
- Pathologic Anatomy of the Pancreas in Juvenile Diabetes MellitusDiabetes, 1965
- Schmidt's Syndrome (Thyroid and Adrenal Insufficiency) and Coexistent Diabetes MellitusDiabetes, 1965
- THEATRE OF ANATOMY, HOLLEN-STREET, WARDOUR-STREET, SOHO.The Lancet, 1824