Plasma Lignocaine Concentrations following Topical Laryngeal Application
Open Access
- 1 February 1983
- journal article
- research article
- Published by SAGE Publications in Anaesthesia and Intensive Care
- Vol. 11 (1) , 23-26
- https://doi.org/10.1177/0310057x8301100105
Abstract
Lignocaine 4%, 4 mg/kg, was sprayed onto the larynx and subglottic area of 96 children aged from 2 weeks to 12 years and plasma lignocaine concentrations were measured. While the majority were well within the accepted safe range (4-5 μg/ml) occasional concentrations over 8 μg/ml appeared in all groups. Simultaneous arterial and venous sampling showed a small but significant difference in the first 10 minutes.Keywords
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