Asymmetric synthesis of a chiral norbornene derivative by lipase-catalyzed transesterification of cis-endo-5-norbornene-2,3-dimethanol and its application to the synthesis of an optically active TXA2 antagonist.
- 1 January 1990
- journal article
- letter
- Published by Pharmaceutical Society of Japan in CHEMICAL & PHARMACEUTICAL BULLETIN
- Vol. 38 (8) , 2329-2331
- https://doi.org/10.1248/cpb.38.2329
Abstract
The asymmetric synthesis of chiral cis-endo-5-norbornene-2, 3-dimethanol mono acetate by lipase-catalyzed transesterification, and it was used to synthesize an optically active TXA2 antagonist.Keywords
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