Diagnostic and Physiologic Implications of the Angiotensin Infusion Test

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Abstract
MUCH effort is currently expended to separate patients with hypertension due to stenosis of the renal arteries from those with hypertension due to diseases that are not amenable to surgical therapy. The tests involved are difficult and have a significant morbidity.Kaplan and Silah1 described a relatively simple procedure that held out promise of differentiating patients with hypertension into those with and without renal-artery stenosis. They noted that patients with stenosis, when given infusions of angiotension II, required a larger dose than patients with essential hypertension to elevate the blood pressure. Eventually, the procedure was simplified to a screening test . . .

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