Structures of agglomerins.
- 1 January 1990
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 43 (10) , 1245-1253
- https://doi.org/10.7164/antibiotics.43.1245
Abstract
Structures of a series of new antibiotics, agglomerins A, B, C, and D, which are active against a variety of anaerobic bacteria, were determined to be 1-acyl-2,3-dihydroxy-1,3-butadiene-1-carboxylic acid, (1 .fwdarw. 3)-.gamma.-lactones, i.e., 2-acyl-4-ylidenetetronic acids with different hydrocarbon chains in the acyl group. Their common chromophore exhibited tautomerism in solution. The relationship of their structure to the activity against anaerobes is discussed.This publication has 0 references indexed in Scilit: