Autoimmune Haemolytic Anaemias in Thailand

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Abstract
Cases (100) of autoimmune hemolytic anemias (AIHA) in Thailand were analyzed. Clinical and immunological aspects of the disease were compared with those described in other parts of the world. Racial differences, especially between Thais and Caucasians, were emphasized. Thai patients show the following distinctions: AIHA tends to occur in people of a younger age group, predominantly in females; a rare occurrence of AIHA of cold-antibody type with an incidence which significantly differs from that in Caucasians; and the autoantibodies consist of more than 1 immunoglobulin class in more than 50% of the cases. Possible factors that might contribute to these differences were discussed.

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