A STUDY OF SERUM PROLACTIN LEVELS IN SCHIZOPHRENIA: COMPARISON OF MALES AND FEMALES
- 1 September 1992
- journal article
- research article
- Published by Wiley in Clinical and Experimental Pharmacology and Physiology
- Vol. 19 (9) , 603-606
- https://doi.org/10.1111/j.1440-1681.1992.tb00511.x
Abstract
1. Serum prolactin levels were measured in large cohorts of schizophrenic patients (67 males and 42 females) and normal subjects (78 males and 42 females). 2. There was no significant differences between the serum prolactin levels of patients and controls, except in the age group 15-29 years. There were no significant differences between the serum prolactin levels of males and females, either among the patients or the control subjects. 3. The rise in serum prolactin levels after the commencement of neuroleptic medication in the patients was greater in females than in males even though the female patients received neuroleptics at lower doses. 4. These data indicate that serum prolactin levels in unmedicated males and females are similar; however, the prolactin response to neuroleptic medication is greater in females than in males.Keywords
This publication has 11 references indexed in Scilit:
- Serum prolactin levels in manic patientsBiological Psychiatry, 1991
- Endocrinology and psychosisBritish Medical Bulletin, 1987
- Growth Hormone and Prolactin Response to Apomorphine in Schizophrenia and the Major Affective DisordersArchives of General Psychiatry, 1984
- Plasma Prolactin Concentrations and Psychopathology in Chronic SchizophreniaArchives of General Psychiatry, 1982
- Oestrogens, Dopamine and MoodThe British Journal of Psychiatry, 1981
- Dopamine inhibition of action potentials in a prolactin secreting cell line is modulated by oestrogenNature, 1979
- Clinical Significance of Plasma Drug and Prolactin Levels During Acute Chlorpromazine Treatment: A Replication StudyThe British Journal of Psychiatry, 1979
- ProlactinNew England Journal of Medicine, 1978
- Serum Prolactin Levels in Unmedicated Schizophrenic PatientsArchives of General Psychiatry, 1974
- Diagnostic Criteria for Use in Psychiatric ResearchArchives of General Psychiatry, 1972