Is there a real treatment for stroke? Clinical and statistical comparison of different treatments in 300 patients.

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Abstract
In the absence of universally accepted criteria for the medical treatment of stroke, a rigorously randomized comparative study was made of different treatments in 300 patients. One group of patients received only a general supportive treatment designed to ensure adequate supplies of water, electrolytes and calories, plus whatever was needed to prevent infection and correct extant associated pathology. Three other groups of patients were treated in the same way but were also given, respectively, one of the following medications: Hydergine (a mixture of 3 ergot alkaloids), dexamethasone and mannitol. No statistically significant difference emerged among any of the treatment groups and the reference group in terms of objective therapeutic results. At least with the dosage used in this study, none of the treatments proved more useful than conventional supportive therapy in the first 10 days after a stroke.