STUDIES IN THE PHYSIOLOGY OF VITAMINS

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Abstract
Tracings of the gastric motility of 7 dogs with simple gastric fistulae were taken at frequent intervals during the progress of and recovery from B-avitaminosis. Blood sugar estimations were also made. The majority of animals manifested a decrease in gastric motility when symptoms of vitamin B deficiency occurred. Insulin was then administered parenterally and in 4 out of 16 experiments, the injection of the hormone was followed by a definite improvement in the motility of the stomach. This response was not due to the presence of vitamin B in the hormone preparation (insulin, Lilly), since a biologic assay showed that the insulin was deficient in this factor. No direct relationship between the blood sugar level and the gastric motility could be demonstrated.

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