Cd bands and centromeric function in dicentric chromosomes
- 1 May 1980
- journal article
- research article
- Published by Springer Nature in Human Genetics
- Vol. 54 (2) , 265-267
- https://doi.org/10.1007/bf00278982
Abstract
The Cd technique was applied to two cases of dicentric attached X chromosomes (XpXp and XqXq) and to cells from an established cell line of tumor origin (MaNo9) in which dicentrics with two active centromeres were present and dicentrics with one active and one inactive centromere. It was confirmed that the Cd technique discriminates between active and latent centromeres, and it was demonstrated that true dicentrics and dicentrics with one latent centromere can co-exist in the same cells. This indicates that the mechanism of centromere inactivation is a phenomenon that is specific to each chromosome and not generalized at the level of the individual cell.This publication has 15 references indexed in Scilit:
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