Comparison of 3′,5′- and 2′,5′-linked DNA duplex stabilities by electrospray ionization mass spectrometry
- 1 January 1996
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- No. 6,p. 747-748
- https://doi.org/10.1039/cc9960000747
Abstract
Two mutually complementary strands of 2′,5′-linked DNA form a unique noncovalent complex observed by electrospray ionization mass spectrometry; by the latter method, the double-stranded state of a 2′,5′-linked DNA duplex is less stable than the natural DNA duplex of identical base composition.Keywords
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