The Induced Rejection of Guinea Pig Skin Homografts by a Partially Purified Transfer Factor
Open Access
- 1 January 1964
- journal article
- research article
- Published by Oxford University Press (OUP) in The Journal of Immunology
- Vol. 92 (1) , 73-81
- https://doi.org/10.4049/jimmunol.92.1.73
Abstract
Summary: The effects of a partially purified transfer factor (PTF) on specific guinea pig skin homografts has been described. There is a significant increase in the rate of rejection of such grafts, compared with controls. PTF taken from nonspecifically stimulated animals is inactive, as is that prepared from second-set recipients. There is no obvious correlation between the size of the cutaneous transfer reaction and the anti-graft activity of these preparations.Keywords
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