Identification and Isolation of Melanoma-Associated Antigens with Monoclonal Antibodies
- 1 January 1982
- journal article
- research article
- Published by Mary Ann Liebert Inc in Hybridoma
- Vol. 1 (4) , 413-421
- https://doi.org/10.1089/hyb.1.1982.1.413
Abstract
The monoclonal antibodies distributed at the first Workshop on Monoclonal Antibodies to Melanoma have been tested by immunoprecipitation, and one group of antigens (90 kd) has been found to be identical by sequential immunoprecipitation. These results are in good agreement with those from other laboratories. In addition, antigens from a new group of hybridomas, generated since the first Workshop, were studied. Some of these antigens are unique and others are duplicates of the original set. Finally, a melanomaassociated antigen (260 kd) was purified by immunoaffinity chromatography.Keywords
This publication has 12 references indexed in Scilit:
- Murine cell surface glycoproteins. Identification, purification, and characterization of a major glycosylated component of 110,000 daltons by use of a monoclonal antibody.Journal of Biological Chemistry, 1982
- GD3, a prominent ganglioside of human melanoma. Detection and characterisation by mouse monoclonal antibody.The Journal of Experimental Medicine, 1982
- Human melanoma-associated antigen p97 is structurally and functionally related to transferrinNature, 1982
- Unique glycoprotein-proteoglycan complex defined by monoclonal antibody on human melanoma cells.Proceedings of the National Academy of Sciences, 1982
- Surface antigens of human melanoma cells defined by monoclonal antibodies. I. Biochemical characterization of two antigens found on cell lines and fresh tumors of diverse tissue originEuropean Journal of Immunology, 1981
- Production and Characterization of Monoclonal Antibody to a Melanoma Specific GlycoproteinHybridoma, 1981
- Cell surface antigens of human malignant melanoma: definition of six antigenic systems with mouse monoclonal antibodies.Proceedings of the National Academy of Sciences, 1980
- Identification of a cell surface protein, p97, in human melanomas and certain other neoplasms.Proceedings of the National Academy of Sciences, 1980
- Study of antibodies against human melanoma produced by somatic cell hybrids.Proceedings of the National Academy of Sciences, 1978
- Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Nature, 1970