Synthesis of Phosphonopeptide Derivatives
- 1 January 1973
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 3 (5) , 375-379
- https://doi.org/10.1080/00397917308063493
Abstract
In 1959, Horiguchi and Kandatsu1 first isolated 2-aminomethylphos-phonic acid from ciliate protozoa. Since then the compound has been found in numerous other organisms2 and recently it has been found in human brain3, liver, heart and skeletal muscles4, and in red blood cell membrane. These findings establish the biological importance of the carbon-phosphorus bond in nature. Quin2 suggested that the naturally occurring aminophosphonic acids are bound to proteins and peptides.Keywords
This publication has 4 references indexed in Scilit:
- 2-Aminoethylphosphonic acid: Distribution in human tissuesBiochimica et Biophysica Acta (BBA) - General Subjects, 1971
- Occurrence of 2-aminoethylphosphonic acid in human brainBiochemistry, 1970
- Isolation of 2-Aminoethane Phosphonic Acid from Rumen ProtozoaNature, 1959
- Über einige synthetisch verwertbare Derivate der AminosäurenEuropean Journal of Inorganic Chemistry, 1908