An in‐vivo study of renal cadmium and hypertension

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Abstract
A comparative study of renal Cd burdens in 30 hypertensive patients undergoing treatment and in 30 matched controls was reported, both groups being volunteers selected from a non-occupationally exposed population. Possible involvement of Cd in etiology of hypertension at chronic low levels of environmental exposure were studied. Renal Cd levels were measured in vivo using partial-body neutron activation analysis. Mean renal Cd level in hypertensive group [3.3 mg (SD 2.3)] was not significantly different from that [4.4 mg (SD 2.7)] in the normotensive group. Whether the level in hypertensives depended on treatment was open to question. Kidney Cd levels were elevated in smokers.