A clinical and immunopathological study of 304 cases of glomerulonephritis in Tunisia

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Abstract
In Tunisia, 304 [human] cases of glomerulonephritis were biopsied and studied morphologically. The incidence of glomerulonephritis with marked proliferation of endocapillary cells was 60%, a figure considerably higher than in other large series. Using a Clq [q fragment of complement component 1 ] binding assay, statistically significant levels of immune complexes were found in cases of acute proliferative glomerulonephritis. Among other types of glomerulonephritis, circulating immune complexes were frequently found in systemic lupus erythematosus but only in a low percentage of primary glomerulonephritis with or without immunoglobulin deposits.