Collagen synthesis by human bone marrow fibroblasts
- 1 December 1987
- journal article
- research article
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 43 (11-12) , 1223-1225
- https://doi.org/10.1007/bf01945534
Abstract
Collagen synthesis was measured in fibroblast cultures derived from normal and acute lymphoblastic leukemia (ALL) bone marrow. Collagen production was higher in normal than in ALL fibroblasts. These cells elaborate type I and type III procollagens in a ratio that depends on cell density and whether cells originate from normal or ALL bone marrow.Keywords
This publication has 17 references indexed in Scilit:
- Collagen Synthesis in Virus‐transformed CellsaAnnals of the New York Academy of Sciences, 1985
- Inhibition of collagen deposition in the extracellular matrix prevents the establishment of a stroma supportive of hematopoiesis in long-term murine bone marrow cultures.Journal of Clinical Investigation, 1985
- Bone Marrow Fibroblasts in Acute Lymphoblastic LeukemiaActa Haematologica, 1985
- Effect of hydrocortisone on the growth of human bone marrow fibroblastsBritish Journal of Haematology, 1982
- Influence of cell density on collagen biosynthesis in fibroblast culturesBiochemical Journal, 1982
- Collagen synthesis by bone marrow stromal cells: a quantitative studyBritish Journal of Haematology, 1982
- Collagen biosynthesis by human skin fibroblasts II. Isolation and further characterization of type I and type III procollagens synthesized in cultureBiochimica et Biophysica Acta (BBA) - Protein Structure, 1980
- High cell density alters the ratio of type III to I collagen synthesis by fibroblastsNature, 1979
- Conditions controlling the proliferation of haemopoietic stem cells in vitroJournal of Cellular Physiology, 1977
- Use of a mixture of proteinase-free collagenases for the specific assay of radioactive collagen in the presence of other proteinsBiochemistry, 1971