BAROREFLEX EFFECTS OF ALTHESIN INFUSIONS TO SUPPLEMENT NITROUS OXIDE ANAESTHESIA IN MAN

Abstract
The effects on baroreflex control of heart rate, of 2 infusion rates of Althesin (18 and 36 .mu.g/kg per min as total steroid) to supplement 66% N2O in O2 anesthesia, were studied in 6 younger (mean age 35.5 yr) and 6 older (mean age 61.0 yr) patients. Steady-state anesthesia at both infusion rates was associated with diminished baroreflex sensitivity and resetting of the reflex to allow lower arterial pressures to be maintained without tachycardia.

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