Potent and specific inhibitors of trypanothione reductase from Trypanosoma cruzi: bis(2-aminodiphenylsulfides) for fluorescent labeling studies
- 30 April 2001
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry
- Vol. 9 (4) , 837-846
- https://doi.org/10.1016/s0968-0896(00)00312-6
Abstract
No abstract availableKeywords
This publication has 17 references indexed in Scilit:
- Down-regulation of Leishmania donovani trypanothione reductase by heterologous expression of a trans-dominant mutant homologue: Effect on parasite intracellular survivalProceedings of the National Academy of Sciences, 1998
- New potent inhibitors of trypanothione reductase from Trypanosoma cruzi in the 2-aminodiphenylsulfide seriesEuropean Journal of Medicinal Chemistry, 1997
- Disruption of the trypanothione reductase gene of Leishmania decreases its ability to survive oxidative stress in macrophagesThe EMBO Journal, 1997
- Synthesis and structure of macrocyclic dioxa-, dithia-, diazatetralactams and derivativesTetrahedron, 1996
- 2-Amino diphenylsulfides as inhibitors of trypanothione reductase: modification of the side chainBioorganic & Medicinal Chemistry, 1996
- 2-Amino diphenylsulfides as new inhibitors of trypanothione reductaseInternational Journal of Antimicrobial Agents, 1995
- METABOLISM AND FUNCTIONS OF TRYPANOTHIONE IN THE KINETOPLASTIDAAnnual Review of Microbiology, 1992
- Substrate specificity of the flavoprotein trypanothione disulfide reductase from Crithidia fasciculataBiochemistry, 1987
- Trypanothione: A Novel Bis(glutathionyl)spermidine Cofactor for Glutathione Reductase in TrypanosomatidsScience, 1985
- Identification of a novel, thiol-containing co-factor essential for glutathione reductase enzyme activity in trypanosomatidsMolecular and Biochemical Parasitology, 1985