Familial Anosmia
- 1 January 1970
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Neurology
- Vol. 22 (1) , 40-44
- https://doi.org/10.1001/archneur.1970.00480190044007
Abstract
WHEN A PATIENT is found to lack the sense of smell, the clinician does not usually consider a genetically-determined etiology. Yet, total anosmia does occur in families. The disorder was first reported by Glaser in 1918.1Two more families have since been reported2,3and several reports of partial anosmia are also on record.4-7The purpose of the present paper is to report a family in which six subjects in three generations had anosmia. Some affected family members also had premature baldness and vascular headaches. The relevant literature is reviewed. Report of Cases The propositus, a 40-year-old Sikh army officer, was referred to the neurology clinic with a chief complaint of episodic severe headaches of 13 years' duration. While eliciting his history, it was discovered that he had lacked the ability to smell for as many years as he could remember. No significant head trauma had occurredKeywords
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