Long- and short-term variability of automated perimetry results in patients with optic neuritis and healthy subjects.

Abstract
THE ABILITY to distinguish visual field progression or improvement from one visit to the next is difficult because of the variability that occurs with threshold measurements, especially in areas of visual field damage. This variability of conventional automated perimetry has been investigated extensively in normal subjects and patients with glaucoma1-6 and is closely related to loss of sensitivity. Beyond approximately 1 log unit (10 dB) of sensitivity loss in patients with glaucoma, variability rises exponentially and encompasses nearly the full measurement range of the instruments used.7 For example, a test location with 15 dB of loss in patients with glaucoma has a 95% prediction interval that ranges from about 5 to 30 dB.

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