A REFORMULATION OF THE SERIALLY ADDITIVE EXPECTED DOSE METHOD FOR OCCUPATIONAL COHORT DATA
- 1 October 1983
- journal article
- research article
- Published by Oxford University Press (OUP) in American Journal of Epidemiology
- Vol. 118 (4) , 592-598
- https://doi.org/10.1093/oxfordjournals.aje.a113664
Abstract
Lubin, J. H. (Environmental Epidemiology Branch, NCI, Bethesda, MD 20205). A reformulation of the serially additive expected dose method for occupational cohort data. Am J Epidemiol 1983; 118: 592–8. The serially additive expected dose method for the analysis of occupational cohort data can be biased whenever worker exposure is associated with length of follow-up. An Illustration shows that this bias can act to either enhance or reduce the degree of association between disease and exposure. The serially additive expected dose method can be modified, then embedded In a classical Cox proportional hazards model context to eliminate the analytic bias. A chisquare test of no exposure association is derived.Keywords
This publication has 1 reference indexed in Scilit:
- EPIDEMIOLOGIC INVESTIGATION OF OCCUPATIONAL CARCINOGENESIS USING A SERIALLY ADDITIVE EXPECTED DOSE MODELAmerican Journal of Epidemiology, 1980