Sudden Death after Myocardial Infarction — Who Needs Prophylaxis, and When?

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Abstract
Although the age-adjusted mortality from cardiovascular disease has declined in recent years, the number of sudden deaths has risen.1 According to data from the Centers for Disease Control and Prevention, 63 percent of deaths from cardiovascular causes in the United States, or more than 450,000 events, in 1998 were sudden and unexpected, most being attributable to coronary disease. Sudden death is the end result of multiple processes, usually manifested electrocardiographically as ventricular fibrillation or ventricular tachycardia.The type of arrhythmia observed depends on the temporal relation to myocardial infarction. In the acute phase of myocardial infarction, the metabolic consequences of . . .