Complementation analysis in fibroblasts from eight patients with clinically different forms of citrullinaemia
- 1 December 1981
- journal article
- research article
- Published by Springer Nature in Journal of Inherited Metabolic Disease
- Vol. 4 (1) , 23-25
- https://doi.org/10.1007/bf02263577
Abstract
We have examined the possibility of genetic heterogeneity in citrullinaemia by measuring the incorporation of [14C]citrulline into protein in PEG-induced heterokaryons derived from paired combinations of fibroblasts from eight patients with varying forms of the disease. The results are compatible with interallelic, but not intergenic, complementation in several of these fusions.This publication has 8 references indexed in Scilit:
- CitrullinemiaVirchows Archiv, 1978
- Biosynthesis of urea. Molecular and regulatory properties of crystalline argininosuccinate synthetase.Journal of Biological Chemistry, 1977
- Studies of Rat Liver Argininosuccinate SynthetaseThe Journal of Biochemistry, 1977
- Citrullinemia, argininosuccinate synthetase deficiencyCytogenetic and Genome Research, 1977
- Citrullinemia: Enzymatic Evidence for Genetic HeterogeneityPediatric Research, 1975
- Citrullinemia: Investigation and treatment over afour-year periodThe Journal of Pediatrics, 1974
- Citrullinemia, Report of a Case, with Studies on Antenatal DiagnosisPediatric Research, 1973
- CitrullinemiaAmerican Journal of Diseases of Children, 1967