Dose-Effect Relationship amongst Three Different Sustained-Release Forms of Isosorbide 5-Mononitrate in Patients with Coronary Artery Disease
- 1 January 1987
- journal article
- clinical trial
- Published by S. Karger AG in Cardiology
- Vol. 74 (1) , 29-33
- https://doi.org/10.1159/000174261
Abstract
Fifteen patients with coronary artery disease and stable angina pectoris were included in a double-blind, randomized, cross-over study. The patients received 25, 50 and 100 mg isosorbide 5-mononitrate, as well as a placebo, for subsequent 1-week periods. On the 7th day of each treatment period, 8 h after medication application, an exercise test was performed. A highly significant (pThis publication has 0 references indexed in Scilit: