A dominant lethal study in male rats after repeated exposures to vinyl chloride or vinylidene chloride
- 1 December 1977
- journal article
- research article
- Published by Taylor & Francis in Journal of Toxicology and Environmental Health
- Vol. 3 (5-6) , 965-968
- https://doi.org/10.1080/15287397709529630
Abstract
Male CD rats were exposed 6 hr/day for 5 days/wk to 0, 50, 250, or 1,000 ppm of vinyl chloride or 55 ppm of vinylidene chloride. Starting on week 11 of exposure, these males were mated with untreated females. There was no evidence of either preimplantation loss or postimplanation loss in pregnant females that resulted from these matings. Consequently, it was concluded that these exposures did not produce germinal mutation, as manifested by a dominant lethal effect, in male rots.This publication has 6 references indexed in Scilit:
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