AN IMPROVED METHOD OF PREPARING CERVICAL ADRENAL TRANSPLANTS IN THE SHEEP
- 1 August 1964
- journal article
- research article
- Published by Wiley in Immunology & Cell Biology
- Vol. 42 (4) , 443-448
- https://doi.org/10.1038/icb.1964.41
Abstract
Summary: Methods previously described for the transplantation of the intact sheep's adranal gland to a cervical skin tube, with preservation of blood supply, have frequently failed because of oedema formation and subsequent venous thrombosis in the loop. In the method described here, the first stage consists of making a large loop containing the carotid artery and jugular vein. Oedema formation occurs as in the old procedure, but subsides within two weeks. It is suggested that a preformed endothelium‐lined pocket could be made with advantage for transplanting organs with a serosal surface. Transplantation of the adrenal gland is performed some three months later and after this procedure, oedema formation is insignificant. Improvements in methods of loop formation, mobilizing the renal vein and in carrying out the vascular anastomoses are described.Keywords
Funding Information
- U.S.P.H.S.
- National Heart Institute (HE 06284)
- N.H.
- M.R.C. of Australia
- Wool Research Trust Fund
- Anti-Cancer Council of Victoria
- Rural Credits Fund of the Reserve Bank
This publication has 3 references indexed in Scilit:
- Blood Flow Through the Adrenal GlandEndocrinology, 1963
- HUMORAL STIMULATION OF ADRENAL CORTICAL SECRETION*Journal of Clinical Investigation, 1962
- THE EFFECT OF PROGRESSIVE SODIUM DEPLETION ON CORTICOSTEROID SECRETION BY THE AUTOTRANSPLANTED ADRENAL GLAND OF CONSCIOUS SHEEPJournal of Endocrinology, 1961