Localization of polymorphic DNA probes frequently deleted in lung carcinoma

Abstract
Five polymorphic DNA segments from human chromosome 3, that are frequently deleted in lung carcinoma were mapped by non-isotopic in situ hybridization to metaphase chromosomes. The DNA segment D3S3 mapped to 3p13–p14.2, D3S6 to 3p14.3–p14.5, D3S48 to distal 3p21–p22, ERBAß to 3p24.3 and ERBA2 to 3p24.3. The map location of ERBAß and ERBA2 was confirmed by re-mapping each probe in combination with D3S6 as a marker for 3p14.