Leaky +1 and −1 frameshift mutations at the same site in a yeast mitochondrial gene
- 1 November 1980
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 288 (5786) , 60-63
- https://doi.org/10.1038/288060a0
Abstract
Two mutations in a mitochondrial structural gene, which cause leaky premature polypeptide chain termination and leaky growth, are +1 and -1 frameshifts in the same run of 5 T residues. The partial restoration of reading frame is probably due to ribosomal frameshifting at this site, and may be promoted by the unique structure of the yeast mitochondrial tRNAPhe.This publication has 30 references indexed in Scilit:
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