Iron, a new aid in the treatment of Parkinson patients
- 1 September 1986
- journal article
- research article
- Published by Springer Nature in Journal Of Neural Transmission-Parkinsons Disease and Dementia Section
- Vol. 67 (3-4) , 287-292
- https://doi.org/10.1007/bf01243354
Abstract
Summary One of the problems in treating Parkinson patients is the so called “off-effect” which occurs after long term treatment with L-DOPA. Off-effects are characterized by severe rigor and akinesia. Increasing dosages of L-DOPA and decarboxylase- or monoaminooxidase-inhibitors do not improve these symptoms. Intravenously applied iron-in form of a ferri-ferro-complex-exhibited a considerable benefit for all patients treated so far. They regained a remarkable mobility. Their disability score dropped from up to 90% down to 30%. The effect of iron is dosage-dependent and lasts 24 to 48 hours.Keywords
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