Chloroacetates of 2- and 3-demethylthiocolchicine: Specific covalent interactions with tubulin with preferential labeling of the β-subunit
- 1 September 1992
- journal article
- Published by Elsevier in Biochemical and Biophysical Research Communications
- Vol. 187 (3) , 1350-1358
- https://doi.org/10.1016/0006-291x(92)90451-p
Abstract
No abstract availableKeywords
This publication has 14 references indexed in Scilit:
- Interactions of colchicine with tubulinPharmacology & Therapeutics, 1991
- Antitubulin effects of derivatives of 3-demethylthiocolchicine, methylthio ethers of natural colchicinoids, and thioketones derived from thiocolchicine. Comparison with colchicinoidsJournal of Medicinal Chemistry, 1990
- Photoaffinity labeling of tubulin with (2-nitro-4-azidophenyl)deacetylcolchicine: direct evidence for two colchicine binding sitesBiochemistry, 1989
- Antimitotic natural products combretastatin A-4 and combretastatin A-2: studies on the mechanism of their inhibition of the binding of colchicine to tubulinBiochemistry, 1989
- Association of thiocolchicine with tubulinBiochemical and Biophysical Research Communications, 1989
- Colchicine and its analogues: Recent findingsMedicinal Research Reviews, 1988
- Synthesis and biological effects of novel thiocolchicines. 3. evaluation of N-acyldeacetylthiocolchicines, N-(alkoxycarbonyl)deacetylthiocolchicines, and O-ethyldemethylthiocolchicines. New synthesis of thiodemecolcine and antileukemic effects of 2-demethyl- and 3-demethylthiocolchicineJournal of Medicinal Chemistry, 1985
- Separation of active tubulin and microtubule-associated proteins by ultracentrifugation and isolation of a component causing the formation of microtubule bundlesBiochemistry, 1984
- Specific affinity labelling of tubulin with bromocolchicineJournal of Molecular Biology, 1976
- High-resolution preparative SDS-polyacrylamide gel electrophoresis: Fluorescent visualization and electrophoretic elution-concentration of protein bandsAnalytical Biochemistry, 1975