Localized Cutaneous Amyloidosis

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Abstract
The subject of amyloidosis has attracted the attention of pathologists and internists for more than 100 years. Rokitansky1 and Virchow2 were among the first to report a pathosis in which various organs were infiltrated by a firm, waxy, translucent, gray, homogeneous substance. Virchow named it amyloid because it gave a vegetable, starch-like reaction after the application of iodine and dilute sulfuric acid. In the last 30 years, dermatologists have written extensively on amyloidosis of the skin. A classification which is more or less accepted by most dermatologists in one which is modified after Michelson and Lynch.3 It is divided into (1) generalized amyloidosis with cutaneous involvement; (2) systematized amyloidosis with cutaneous lesions, and (3) localized amyloidosis of the skin— primary and secondary. In the case of the generalized variety, it was promptly recognized to be associated with long-standing suppurative disease of bone, with syphilis,

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