Detection of patients with hypertrophic cardiomyopathy at risk for paroxysmal atrial fibrillation during sinus rhythm by P‐wave dispersion

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Abstract
Background: Paroxysmal atrial fibrillation (PAF) in hypertrophic cardiomyopathy (HCM) is associated with poor prognosis. Previous studies have shown good correlation between P‐wave dispersion (Pd) and occurrence of PAF. However, Pd in patients with HCM for predicting PAF has not been studied.Hypothesis: The aim of the study was to determine whether Pd could identify patients with HCM who are likely to suffer from PAF.Methods: Twenty‐two patients with HCM with a history of PAF (Group 1) and 26 patients with HCM without a history of PAF (Group 2) were studied. Maximum (Pmax) and minimum (Pmin) P‐wave durations, as well as P‐wave dispersion (Pd = Pmax‐Pmin) were calculated from 12‐lead surface electrocardiograms (ECG).Results: P‐wave dispersion was significantly different between the groups (Group 1:55 ± 6 msvs. Group 2:37 ± 8 ms; pConclusion: This study suggests that P‐wave dispersion could identify patients withHCM who are likely to develop PAF.