Prospects for human papillomavirus vaccine development: emerging HPV vaccines
- 1 February 1998
- journal article
- review article
- Published by Wolters Kluwer Health in Current Opinion in Obstetrics and Gynecology
- Vol. 10 (1) , 15-19
- https://doi.org/10.1097/00001703-199802000-00004
Abstract
This review concentrates on recent advances in human papillomavirus vaccine development. Strategies for prophylactic HPV subunit vaccines utilizing recombinantly synthesized, immunogenic virus-like particles are discussed. Therapeutic strategies focusing on the induction of cell-mediated immunity and gene manipulation for the treatment of established HPV-associated disease are also reviewed.*Keywords
This publication has 35 references indexed in Scilit:
- Antisense targeting of E6AP elevates p53 in HPV-infected cells but not in normal cellsOncogene, 1997
- Analysis of Cytokine Profiles in Patients With Human Papillomavirus-Associated NeoplasmsJNCI Journal of the National Cancer Institute, 1997
- In VitroAntigene Therapy Targeting HPV-16 E6 and E7 in Cervical CarcinomaGynecologic Oncology, 1997
- Adenovirus-Mediated Transfer of HPV 16E6/E7Antisense RNA to Human Cervical Cancer CellsGynecologic Oncology, 1996
- Prevalence of Human Papillomavirus in Cervical Cancer: a Worldwide PerspectiveJNCI Journal of the National Cancer Institute, 1995
- Role of Conformational Epitopes Expressed by Human Papillomavirus Major Capsid Proteins in the Serologic Detection of Infection and Prophylactic VaccinationGynecologic Oncology, 1994
- The Expressed L1 Proteins of HPV-1 HPV-6, and HPV-11 Display Type-Specific Epitopes with Native Conformation and Reactivity with Neutralizing and Nonneutralizing AntibodiesPathobiology, 1994
- Vaccination with cytotoxic T lymphocyte epitope‐containing peptide protects against a tumor induced by human papillomavirus type 16‐transformed cellsEuropean Journal of Immunology, 1993
- p53, guardian of the genomeNature, 1992
- Human Papillomavirus Infection of the CervixObstetrics & Gynecology, 1992