In 1922 I wrote that with painstaking and intelligent care most cases of infantile eczema can be cured entirely. In 1934 I said that the treatment of eczema may be summarized in six words: "Find the cause and remove it." These statements were due to the optimism of youth. The condition in many cases cannot be cured entirely, and finding the cause does not happen as often as the books tell us. In 1948 I say, "Infantile eczema is a perplexing and exasperating disease to treat, and I wish I understood it better." When one is treating an infant with eczema one is dealing with a patient who is diligently and ingeniously working against him twenty-four hours a day; no skin can heal when it is continually rubbed and scratched. Another difficulty is that atopic dermatitis, which comprises about 75 per cent of "eczema" in the young, has as its