An Improved One-Pot Method for the Preparation of 2-Substituted 1H-Perimidines
- 1 November 1991
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 21 (21) , 2171-2180
- https://doi.org/10.1080/00397919108055450
Abstract
2-substituted 1H-perimidines are readily prepared, in high yields, by refluxing a mixture of sodium pyrosulfite, an aldehyde, and 1, 8-diaminonaphthalene in aqueous ethanol or N, N-dimethylformamide. The method is of wide applicability except from araldehydes bearing a strong electron-withdrawing group (-CN, -NO2).Keywords
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