The influence of aminonucleoside on polysome patterns of rat liver

Abstract
Intravenous injection of the aminonucleoside of puromycin has been shown to affect the size distribution of polysomes isolated from rat liver. A marked shift to higher aggregates has been observed in both free and membrane-bound polysomes, with a more pronounced shift in the free polysomes. The shift to higher aggregates was observed by both density gradient and analytical ultracentrifugation analyses.

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