A PROSPECTIVE STUDY OF URINARY PROTEINS IN EARLY INFANCY

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Abstract
Urinary concentrations of protein, albumin, .beta.2-microglobulin, .alpha.-amino nitrogen, and creatinine were determined in 41 full-term infants on 7 occasions up to 6 mo. of age. Except for .beta.2-microglobulin, the concentrations were highest on the 1st day, followed by a rapid decrease to a constant level within 2 wk. Protein diminished approximately 7-fold, albumin 20-fold, .alpha.-amino nitrogen 3-fold and creatinine 5-fold. .beta.2-microglobulin, a low MW protein, first increased 3-fold between day 1 and day 5, thereafter decreasing slowly 17-fold during the first 3 mo. of age. Different kidney functions appear to mature asynchronously.

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